product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human OSCAR protein
catalog :
ATGP3806
quantity :
10 ug
price :
105 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human OSCAR protein
Domain :
19-282aa
Catalog number (SKU) :
ATGP3806
NCBI :
NP_001269278
Description :
OSCAR, also known as osteoclast-associated immunoglobulin-like receptor isoform 6, is an activating receptor expressed by human myeloid cells. It is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes. It is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Its expression is detected specifically in preosteoclasts or mature osteoclasts. It is upregulated on monocytes from rheumatoid arthritis (RA) patients with active disease, and these monocytes show an increased proosteoclastogenic potential. Recombinant human OSCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Osteoclast-associated immunoglobulin-like receptor isoform 6, OSCAR, PIgR-3, PIGR3
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Schultz HS., et al. (2016) Eur J Immunol. 46:952-963.;;Zhou L., et al. (2016) Blood. 127:529-537.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
29.2 kDa (270aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
DITPSVPPAS YHPKPWLGAQ PATVVTPGVN VTLRCRAPQP AWRFGLFKPG EIAPLLFRDV SSELAEFFLE EVTPAQGGSY RCCYRRPDWG PGVWSQPSDV LELLVTEELP RPSLVALPGP VVGPGANVSL RCAGRLRNMS FVLYREGVAA PLQYRHSAQP WADFTLLGAR APGTYSCYYH TPSAPYVLSQ RSEVLVISWE GEGPEARPAS SAPGMQAPGP PPSDPGAQAP SLSSFRPRGL VLQPLLPQTQ DSWDPAPPPS DPGV
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Asp19
Product Type Name :
Recombinant Protein
UniProt No. :
Q8IYS5
Internal Search Terms :
OSCAR, Osteoclast-associated immunoglobulin-like receptor isoform 6 , OSCAR, PIgR-3, PIGR3,ATGP3806-10ug,ATGP3806-20ug,ATGP3806-50ug,ATGP3806-100ug,ATGP3806-250ug,ATGP3806-500ug,ATGP3806-1mg,ATGP3806-10,ATGP3806-20,ATGP3806-50,ATGP3806-100,ATGP3806-250,ATGP3806-500,ATGP3806-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.