product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human SIRP beta 1/CD172b protein
catalog :
ATGP3805
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human SIRP beta 1/CD172b protein
Domain :
30-371aa
Catalog number (SKU) :
ATGP3805
NCBI :
NP_006056
Description :
SIRPB1, also known as signal-regulatory protein beta-1 isoform 1, is a type I transmembrane protein of SIRP superfamily. It is an immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein also participates in the recruitment of tyrosine kinase SYK. And it acts as an activating isoform of SIRP alpha molecules that recruit SHP-1 and SHP-2 protein tyrosine phosphatases and activate counterparts, whose engagement couples to protein tyrosine kinases. Recombinant human SIRPB1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Signal-regulatory protein beta-1 isoform 1, SIRPB1, CD172b, SIRP-BETA-1
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Liu Y., et al, (2005) J Biol Chem. 280:36132-36140.;;Gaikwad S., et al, (2009) Am J Pathol. 175:2528-2539.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
38kDa (348aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
EDELQVIQPE KSVSVAAGES ATLRCAMTSL IPVGPIMWFR GAGAGRELIY NQKEGHFPRV TTVSELTKRN NLDFSISISN ITPADAGTYY CVKFRKGSPD DVEFKSGAGT ELSVRAKPSA PVVSGPAVRA TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGDSVSYSIH STARVVLTRG DVHSQVICEI AHITLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRAENQAN VTCQVSNFYP RGLQLTWLEN GNVSRTETAS TLIENKDGTY NWMSWLLVNT CAHRDDVVLT CQVEHDGQQA VSKSYALEIS AHQKEHGSDI THEAALAPTA PL
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Glu30
Product Type Name :
Recombinant Protein
UniProt No. :
O00241
Internal Search Terms :
SIRP b1, CD172b,ATGP3805-10ug,ATGP3805-20ug,ATGP3805-50ug,ATGP3805-100ug,ATGP3805-250ug,ATGP3805-500ug,ATGP3805-1mg,ATGP3805-10,ATGP3805-20,ATGP3805-50,ATGP3805-100,ATGP3805-250,ATGP3805-500,ATGP3805-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.