product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human DR6/TNFRSF21 protein
catalog :
ATGP3803
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human DR6/TNFRSF21 protein
Domain :
42-349aa
Catalog number (SKU) :
ATGP3803
NCBI :
NP_055267
Description :
TNFRSF21, also known as tumor necrosis factor receptor superfamily member 21, is a transmembrane protein in the TNF receptor superfamily. It promotes apoptosis through the activation of NF-kappa-B pathway. Binding of N-terminal APP (N-APP) and TNFRSF21 triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). This protein plays a role in signaling cascades triggered by stimulation of T-cell receptor. Recombinant human TNFRSF21 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Tumor necrosis factor receptor superfamily member 21, TNFRSF21, BM-018, CD358, DR6, Death receptor 6
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 0.1mM PMSF.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Wang Y., et al, (2015) J Mol Neurosci. 56:966-976.;;Fujikura D., et al, (2017) Nat Commun. 8:13957.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
60.4 kDa (547aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
QPEQKASNLI GTYRHVDRAT GQVLTCDKCP AGTYVSEHCT NTSLRVCSSC PVGTFTRHEN GIEKCHDCSQ PCPWPMIEKL PCAALTDREC TCPPGMFQSN ATCAPHTVCP VGWGVRKKGT ETEDVRCKQC ARGTFSDVPS SVMKCKAYTD CLSQNLVVIK PGTKETDNVC GTLPSFSSST SPSPGTAIFP RPEHMETHEV PSSTYVPKGM NSTESNSSAS VRPKVLSSIQ EGTVPDNTSS ARGKEDVNKT LPNLQVVNHQ QGPHHRHILK LLPSMEATGG EKSSTPIKGP KRGHPRQNLH KHFDINEH
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Gln42
Product Type Name :
Recombinant Protein
UniProt No. :
O75509
Internal Search Terms :
DR6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21, TNFRSF21, BM-018, CD358, DR6,ATGP3803-10ug,ATGP3803-20ug,ATGP3803-50ug,ATGP3803-100ug,ATGP3803-250ug,ATGP3803-500ug,ATGP3803-1mg,ATGP3803-10,ATGP3803-20,ATGP3803-50,ATGP3803-100,ATGP3803-250,ATGP3803-500,ATGP3803-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.