Recombinant human FGF-21 (L174P) protein | NKMAX ATGP3789 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FGF-21 (L174P) protein

catalog :

ATGP3789

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FGF-21 (L174P) protein

Domain :

29-209aa

Catalog number (SKU) :

ATGP3789

NCBI :

NP_061986

Description :

FGF-21 is a unique member of FGF super family that is reported to be primarily produced by the liver. FGF-21 has recently been shown to have beneficial effects on a variety of metabolic parameters, including glucose and lipid metabolism and insulin sensitivity in animal models and is thought to exert potent antidiabetic and lipid-lowering agent of obesity and type 2 diabetes mellitus. FGF-21 activity depends on membrane protein beta Klotho that physically complexes with various FGF receptors, thus conferring them the ability to bind FGF-21 and activate downstream signaling pathways. Recombinant human FGF-21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Fibroblast growth factor 21

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dostalova I., et al. (2009) Physiol Res. 58(1):1-7;;Kharitonenkov A., et al. (2008) BioDrugs. 22(1):37-44.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

21.6 kDa (202aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPAPPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NSA1

Internal Search Terms :

FGF21 (L174P), Fibroblast growth factor 21,ATGP3789-10ug,ATGP3789-20ug,ATGP3789-50ug,ATGP3789-100ug,ATGP3789-250ug,ATGP3789-500ug,ATGP3789-1mg,ATGP3789-10,ATGP3789-20,ATGP3789-50,ATGP3789-100,ATGP3789-250,ATGP3789-500,ATGP3789-1

more info or order :

NKMAX product webpage