Recombinant human CD44 protein | NKMAX ATGP3785 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD44 protein

catalog :

ATGP3785

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD44 protein

Domain :

21-220aa

Catalog number (SKU) :

ATGP3785

NCBI :

NP_000601

Description :

CD44, also known as CD44 antigen isoform 1, is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. The most extensively characterized ligand for CD44 is hyaluronan, a component of the extracellular matrix. It is expressed on the majority of immune cells. The binding of CD44 to hyaluronan is induced on T lymphocytes after activation by antigen and on monocytes after stimulation by inflammatory agents. It improves the prognostic efficacy of tumor differentiation. It might be determinant of differentiation characteristics, imparting properties of increased self-renewal, migration, and invasion. Also it involved in lymphocyte activation, recirculation and homing, and hematopoiesis. Recombinant human CD44, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, LHR, MDU2, MDU3, MIC4

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jackson DG., et al. (1992) Biol Chem. 267:4732-4739.;;Morine Y., et al. (2017) Anticancer Res. 37:5701-5705.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

49 kDa (439aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP LEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln21

Product Type Name :

Recombinant Protein

UniProt No. :

P16070

Internal Search Terms :

CD44, CD44 antigen isoform 1, CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1,ATGP3785-10ug,ATGP3785-20ug,ATGP3785-50ug,ATGP3785-100ug,ATGP3785-250ug,ATGP3785-500ug,ATGP3785-1mg,ATGP3785-10,ATGP3785-20,ATGP3785-50,ATGP3785-100,ATGP3785-250,ATGP3785-500,ATGP3785-1

more info or order :

NKMAX product webpage