Recombinant mouse Biglycan protein | NKMAX ATGP3775 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Biglycan protein

catalog :

ATGP3775

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Biglycan protein

Domain :

38-369aa

Catalog number (SKU) :

ATGP3775

NCBI :

NP_031568

Description :

Bgn, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It binds to the growth factors BMP-4 and influences BMP-4 bioactivity. It plays an important role in stabilizing fibrotic scars after experimental myocardial infarction. It may function in connective tissue metabolism by binding to collagen fibrils and TGF-beta and may promote neuronal survival. Its ablation improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload. It is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Recombinant mouse Bgn, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Biglycan, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Beetz N., et al. (2016) J Mol Cell Cardiol. 101:145-155.;;Bianco P., et al. (1990) J Histochem Cytochem. 38:1549-1563.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Signal Transduction

Molecular Weight :

64.6 kDa (574aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPDEEASGS DTTSGVPDLD SVTPTFSAMC PFGCHCHLRV VQCSDLGLKT VPKEISPDTT LLDLQNNDIS ELRKDDFKGL QHLYALVLVN NKISKIHEKA FSPLRKLQKL YISKNHLVEI PPNLPSSLVE LRIHDNRIRK VPKGVFSGLR NMNCIEMGGN PLENSGFEPG AFDGLKLNYL RISEAKLTGI PKDLPETLNE LHLDHNKIQA IELEDLLRYS KLYRLGLGHN QIRMIENGSL SFLPTLRELH LDNNKLSRVP AGLPDLKLLQ VVYLHSNNIT KVGINDFCPM GFGVKRAYYN GISLFNNPVP YWEVQPATFR CVTDRLAIQF GNYKKLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P28653

Internal Search Terms :

Biglycan, Biglycan, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A,ATGP3775-10ug,ATGP3775-20ug,ATGP3775-50ug,ATGP3775-100ug,ATGP3775-250ug,ATGP3775-500ug,ATGP3775-1mg,ATGP3775-10,ATGP3775-20,ATGP3775-50,ATGP3775-100,ATGP3775-250,ATGP3775-500,ATGP3775-1

more info or order :

NKMAX product webpage