Recombinant human TLR3 protein | NKMAX ATGP3761 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TLR3 protein

catalog :

ATGP3761

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TLR3 protein

Domain :

23-704aa

Catalog number (SKU) :

ATGP3761

NCBI :

NP_003256

Description :

TLR3, also known as toll-like receptor 3, is a member of the toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. It is innate immune receptors for sensing microbial molecules and damage-associated molecular patterns released from host cells. It recognizes dsRNA and activation of the receptor induces the activation of NF-kappaB and the production of type I interferons (IFNs). Its signaling activation is associated with ischemic preconditioning-induced protection against brain ischemia and attenuation of reactive astrogliosis. It is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. Recombinant human TLR3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Toll-like receptor 3, TLR3, CD283, IIAE2

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Alexopoulou L., et al. (2001) Nature. 413:732-738.;;Cole JE., et al. (2011) Proc Natl Acad Sci U S A. 108:2372-2377.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

78.5 kDa (690aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

SSTTKCTVSH EVADCSHLKL TQVPDDLPTN ITVLNLTHNQ LRRLPAANFT RYSQLTSLDV GFNTISKLEP ELCQKLPMLK VLNLQHNELS QLSDKTFAFC TNLTELHLMS NSIQKIKNNP FVKQKNLITL DLSHNGLSST KLGTQVQLEN LQELLLSNNK IQALKSEELD IFANSSLKKL ELSSNQIKEF SPGCFHAIGR LFGLFLNNVQ LGPSLTEKLC LELANTSIRN LSLSNSQLST TSNTTFLGLK WTNLTMLDLS YNNLNVVGND SFAWLPQLEY FFLEYNNIQH LFSHSLHGLF NVRYLNLKRS FTKQSISLAS LPKIDDFSFQ WLKCLEHLNM EDNDIPGIKS NMFTGLINLK YLSLSNSFTS LRTLTNETFV SLAHSPLHIL NLTKNKISKI ESDAFSWLGH LEVLDLGLNE IGQELTGQEW RGLENIFEIY LSYNKYLQLT RNSFALVPSL QRLMLRRVAL KNVDSSPSPF QPLRNLTILD LSNNNIANIN DDMLEGLEKL EILDLQHNNL ARLWKHANPG GPIYFLKGLS HLHILNLESN GFDEIPVEVF KDLFELKIID LGLNNLNTLP ASVFNNQVSL KSLNLQKNLI TSVEKKVFGP AFRNLTELDM RFNPFDCTCE SIAWFVNWIN ETHTNIPELS SHYLCNTPPH YHGFPVRLFD TSSCKDSAPF ELLEHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ser23

Product Type Name :

Recombinant Protein

UniProt No. :

O15455

Internal Search Terms :

TLR3, Toll-like receptor 3, TLR3, CD283, IIAE2,ATGP3761-10ug,ATGP3761-20ug,ATGP3761-50ug,ATGP3761-100ug,ATGP3761-250ug,ATGP3761-500ug,ATGP3761-1mg,ATGP3761-10,ATGP3761-20,ATGP3761-50,ATGP3761-100,ATGP3761-250,ATGP3761-500,ATGP3761-1

more info or order :

NKMAX product webpage