product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse HPD protein
catalog :
ATGP3760
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse HPD protein
Domain :
1-393aa
Catalog number (SKU) :
ATGP3760
NCBI :
NP_032303
Description :
Hpd, also known as 4-hydroxyphenylpyruvate dioxygenase, is a Fe-containing enzyme that catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Existing as a homodimer, Hpd uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding Hpd are the cause of tyrosinemia type 3 and hawkinsinuria, both of which are inborn errors of metabolism that are associated with a variety of symptoms, including mental retardation and seizures and hair and urine abnormalities. Recombinant mouse Hpd protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
4-hydroxyphenylpyruvate dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf, 4-hydroxyphenylpyruvic acid oxidase, HPPDase, F Alloantigen, F protein
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Wada GH., et al. (1975) J Biol Chem J. 250(17):6720-6.;;Endo F., et al. (1997) J Biol Chem. 26;;272(39):24426-32.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Metabolism
Molecular Weight :
47.4 kDa (416aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MTTYNNK GPKPERGRFL HFHSVTFWVG NAKQAASFYC NKMGFEPLAY RGLETGSREV VSHVIKQGKI VFVLCSALNP WNKEMGDHLV KHGDGVKDIA FEVEDCDHIV QKARERGAKI VREPWVEQDK FGKVKFAVLQ TYGDTTHTLV EKINYTGRFL PGFEAPTYKD TLLPKLPRCN LEIIDHIVGN QPDQEMQSAS EWYLKNLQFH RFWSVDDTQV HTEYSSLRSI VVTNYEESIK MPINEPAPGR KKSQIQEYVD YNGGAGVQHI ALKTEDIITA IRHLRERGTE FLAAPSSYYK LLRENLKSAK IQVKESMDVL EELHILVDYD EKGYLLQIFT KPMQDRPTLF LEVIQRHNHQ GFGAGNFNSL FKAFEEEQAL RGNLTDLEPN GVRSGM
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P49429
Internal Search Terms :
Hpd, 4-hydroxyphenylpyruvate dioxygenase, 4HPPD, Fla, Flp, Hppd, Laf,ATGP3760-10ug,ATGP3760-20ug,ATGP3760-50ug,ATGP3760-100ug,ATGP3760-250ug,ATGP3760-500ug,ATGP3760-1mg,ATGP3760-10,ATGP3760-20,ATGP3760-50,ATGP3760-100,ATGP3760-250,ATGP3760-500,ATGP3760-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.