Recombinant human EDAR protein | NKMAX ATGP3759 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human EDAR protein

catalog :

ATGP3759

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human EDAR protein

Domain :

27-187aa

Catalog number (SKU) :

ATGP3759

NCBI :

NP_071731

Description :

EDAR, also known as tumor necrosis factor receptor superfamily member EDAR, is a single-pass type 1 transmembrane protein which is a member of TNF receptor superfamily. This protein was expressed reiteratively in signaling centers regulating key steps in morphogenesis. Also, it is a cell surface receptor for ectodysplasin A which plays an important role in the development of ectodermal tissues such as the skin. Also, defects in EDAR are a cause of ectodermal dysplasia anhidrotic (EDA), also known ectodermal dysplasia hypohidrotic autosomal recessive (HED). Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structure. Recombinant human EDAR, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tumor necrosis factor receptor superfamily member EDAR, EDAR, DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kumar A., et al., (2000) J. Biol. Chem. 276:2668-2677.;;Schneider P, et al., (2001) J. Biol. Chem. 276:18819-18827.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

45.6 kDa (413aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPEYSNCGE NEYYNQTTGL CQECPPCGPG EEPYLSCGYG TKDEDYGCVP CPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPP NTKECVGATS GASANFPGTS GSSTLSPFQH AHKELSGQGH LATAAAAFES RACSLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UNE0

Internal Search Terms :

EDAR, Tumor necrosis factor receptor superfamily member EDAR, EDAR, DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1,ATGP3759-10ug,ATGP3759-20ug,ATGP3759-50ug,ATGP3759-100ug,ATGP3759-250ug,ATGP3759-500ug,ATGP3759-1mg,ATGP3759-10,ATGP3759-20,ATGP3759-50,ATGP3759-100,ATGP3759-250,ATGP3759-500,ATGP3759-1

more info or order :

NKMAX product webpage