Recombinant human JAM-B/VE-JAM protein | NKMAX ATGP3758 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human JAM-B/VE-JAM protein

catalog :

ATGP3758

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human JAM-B/VE-JAM protein

Domain :

29-238aa

Catalog number (SKU) :

ATGP3758

NCBI :

NP_067042

Description :

JAM2, also known as junctional adhesion molecule B isoform 1, is a type 1 transmembrane receptor belonging to the immunoglobulin superfamily. This protein is expressed prominently on high endothelial venules of lymphoid organs where it is localized to the intercellular boundaries of high endothelial cells. It can function as an adhesive ligand for the T cell line J45 and can interact with GM-CSF/IL-4-delived peripheral blood dendritic cells. Also, it plays a role in the regulation of transendothelial migration. It binds to very late activation antigen (VLA) -4, a leucocyte integrin that contributes to rolling and firm adhesion of lymphocytes to endothelial cells through binding to vascular cell adhesion molecule (VCAM) -1. Recombinant human JAM2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Junctional adhesion molecule B isoform 1, JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Palmeri D., et al, (2000) J. Biol. Chem. 275:19139-19145.;;Cunningham SA., et al, (2000) J. Biol. Chem. 275:34750-34756.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

50.7 kDa (452aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPFSAPKDQ QVVTAVEYQE AILACKTPKK TVSSRLEWKK LGRSVSFVYY QQTLQGDFKN RAEMIDFNIR IKNVTRSDAG KYRCEVSAPS EQGQNLEEDT VTLEVLVAPA VPSCEVPSSA LSGTVVELRC QDKEGNPAPE YTWFKDGIRL LENPRLGSQS TNSSYTMNTK TGTLQFNTVS KLDTGEYSCE ARNSVGYRRC PGKRMQVDDL NISLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P57087

Internal Search Terms :

JAM-B, VE-JAM, Junctional adhesion molecule B isoform 1, JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM,ATGP3758-10ug,ATGP3758-20ug,ATGP3758-50ug,ATGP3758-100ug,ATGP3758-250ug,ATGP3758-500ug,ATGP3758-1mg,ATGP3758-10,ATGP3758-20,ATGP3758-50,ATGP3758-100,ATGP3758-250,ATGP3758-500,ATGP3758-1

more info or order :

NKMAX product webpage