Recombinant human LRG1 protein | NKMAX ATGP3755 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human LRG1 protein

catalog :

ATGP3755

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human LRG1 protein

Domain :

36-347aa

Catalog number (SKU) :

ATGP3755

NCBI :

NP_443204

Description :

LRG1, also known as leucine-rich alpha-2-glycoprotein, is a member of leucine-rich repeat (LRR) family. It is neutrophilic expressed during granulocyte differentiation. It has been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. It binds directly to the TGF-beta accessory receptor endoglin, which, in the presence of TGF-beta1, results in promotion of the pro-angiogenic Smad1/5/8 signaling pathway. It promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. It is a key physiological regulator of dendrite complexity of hippocampal pyramidal neurons. It physically interacts with TrkB and attenuates BDNF signaling. Recombinant human LRG1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Leucine-rich alpha-2-glycoprotein, LRG1, HMFT1766, LRG

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wang X., et al. (2013) Nature. 499:306-311.;; O Donnell LC., et al. (2002) J Leukoc Biol. 72:478-485.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

35.4 kDa (321aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

VTLSPKD CQVFRSDHGS SISCQPPAEI PGYLPADTVH LAVEFFNLTH LPANLLQGAS KLQELHLSSN GLESLSPEFL RPVPQLRVLD LTRNALTGLP PGLFQASATL DTLVLKENQL EVLEVSWLHG LKALGHLDLS GNRLRKLPPG LLANFTLLRT LDLGENQLET LPPDLLRGPL QLERLHLEGN KLQVLGKDLL LPQPDLRYLF LNGNKLARVA AGAFQGLRQL DMLDLSNNSL ASVPEGLWAS LGQPNWDMRD GFDISGNPWI CDQNLSDLYR WLQAQKDKMF SQNDTRCAGP EAVKGQTLLA VAKSQ

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P02750

Internal Search Terms :

LRG1, Leucine-rich alpha-2-glycoprotein, LRG1, HMFT1766, LRG,ATGP3755-10ug,ATGP3755-20ug,ATGP3755-50ug,ATGP3755-100ug,ATGP3755-250ug,ATGP3755-500ug,ATGP3755-1mg,ATGP3755-10,ATGP3755-20,ATGP3755-50,ATGP3755-100,ATGP3755-250,ATGP3755-500,ATGP3755-1

more info or order :

NKMAX product webpage