Recombinant human CD3 zeta/CD247 protein | NKMAX ATGP3754 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD3 zeta/CD247 protein

catalog :

ATGP3754

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD3 zeta/CD247 protein

Domain :

52-164aa

Catalog number (SKU) :

ATGP3754

NCBI :

NP_932170.1

Description :

CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247

Concentration :

0.2mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 6.8) containing 50% glycerol, 1mM DTT, 1mM EDTA, 0.1M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tomita K., et al. (2001) J. Biol. Chem. 276:25378-25385.;; Li R., et al. (2012) Lupus. 21:75-83.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

14.1 kDa (122aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

RVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P20963

Internal Search Terms :

TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10ug, ATGP3754-20ug, ATGP3754-50ug, ATGP3754-100ug, ATGP3754-250ug, ATGP3754-500ug, ATGP3754-1mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M

more info or order :

NKMAX product webpage