Recombinant human MBL protein | NKMAX ATGP3749 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MBL protein

catalog :

ATGP3749

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MBL protein

Domain :

21-248aa

Catalog number (SKU) :

ATGP3749

NCBI :

NP_000233.1

Description :

MBL2, also known as mannose-binding protein C, belongs to the class of collectins in the C-type lectin superfamily. It is a lectin that is instrumental in innate immunity via the lectin pathway. It recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. It It binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes. This protein has recently been found to play a role in development of type 1 diabetes and gestational diabetes mellitus. Also, mutant MBL2 haplotypes have been linked to disease progression and response to therapy in HCV infection. Recombinant human MBL2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Mannose binding lectin 2, MBL, Collectin 1, Mannose-binding protein, COLEC1, MBP-C, MBP1, MBP

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tomaiuolo R., et al. (2012) Aging Cell. 11:394-400.;; Stuart LM., et al. (2005) J Immunol. 174:3220-3226.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

25.1 kDa (237aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ETVTCED AQKTCPAVIA CSSPGINGFP GKDGRDGTKG EKGEPGQGLR GLQGPPGKLG PPGNPGPSGS PGPKGQKGDP GKSPDGDSSL AASERKALQT EMARIKKWLT FSLGKQVGNK FFLTNGEIMT FEKVKALCVK FQASVATPRN AAENGAIQNL IKEEAFLGIT DEKTEGQFVD LTGNRLTYTN WNEGEPNNAG SDEDCVLLLK NGQWNDVPCS TSHLAVCEFP I

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P11226

Internal Search Terms :

MBL2, Mannose-binding protein C, MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD,ATGP3749-10ug,ATGP3749-20ug,ATGP3749-50ug,ATGP3749-100ug,ATGP3749-250ug,ATGP3749-500ug,ATGP3749-1mg,ATGP3749-10,ATGP3749-20,ATGP3749-50,ATGP3749-100,ATGP3749-250,ATGP3749-500,ATGP3749-1

more info or order :

NKMAX product webpage