product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human S6K1/RPS6KB1 protein
catalog :
ATGP3741
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human S6K1/RPS6KB1 protein
Domain :
1-525aa,Human
Catalog number (SKU) :
ATGP3741
NCBI :
NP_003152
Description :
RPS6KB1, also known as ribosomal protein S6 kinase beta-1 isoform a, is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. Phosphorylation of S6 induces protein synthesis at the ribosome. The phosphorylation of p70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations. However, several recent studies suggest that the activity of p70S6K plays a more positive role in the increase of autophagy. Recombinant human RPS6KB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
STK14A, Serine/threonine-protein kinase 14A, S6K-beta-1, S6K1, S6K, RPS6KB1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1 isoform a, PS6K, P70S6K1, p70-S6K, p70-alpha, p70(S6K)-alpha, p70 S6KA, p70 S6 kinase alpha, p70 ribosomal S6 kinase alpha, 70 kDa ribosomal protein S6 kinase 1
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 50mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.5M NaCl, 2mM DTT, 0.1mM PMSF
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Grove JR., et al, (1991) Mol Cell Biol. 11:5541-5550.;; Ferrari S., et al, (1994) Crit Rev Biochem Mol Biol. 29:385-413.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
60.2 kDa (533aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MRRRRRRDGF YPAPDFRDRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL NESMDHGGVG PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC KESIHDGTVT HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP FFRHINWEEL LARKVEPPFK PLLQSEEDVS QFDSKFTRQT PVDSPDDSTL SESANQVFLG FTYVAPSVLE SVKEKFSFEP KIRSPRRFIG SPRTPVSPVK FSPGDFWGRG ASASTANPQT PVEYPMETSG IEQMDVTMSG EASAPLPIRQ PNSGPYKKQA FPMISKRPEH LRMNL
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met1
Product Type Name :
Recombinant Protein
UniProt No. :
P23443
Internal Search Terms :
RPS6KB1, Ribosomal protein S6 kinase beta-1 isoform a, RPS6KB1, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, PS6K, S6K, S6K-beta-1, S6K1, STK14A,ATGP3741-10ug,ATGP3741-20ug,ATGP3741-50ug,ATGP3741-100ug,ATGP3741-250ug,ATGP3741-500ug,ATGP3741-1mg,ATGP3741-10,ATGP3741-20,ATGP3741-50,ATGP3741-100,ATGP3741-250,ATGP3741-500,ATGP3741-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.