Recombinant human CD147/BSG protein | NKMAX ATGP3737 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD147/BSG protein

catalog :

ATGP3737

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD147/BSG protein

Domain :

22-207aa

Catalog number (SKU) :

ATGP3737

NCBI :

NP_940991

Description :

BSG, also known as basigin isoform 2, is a type 1 transmembrane protein with various different N- and O- glycosylation that belongs to the immunoglobulin superfamily. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, it is thought also to play a role in intercellular recognition. This protein has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins and regulates several distinct functions, such as spermatogenesis, expression of the mono-carboxylate transporter and the responsiveness of lymphocytes. Also, it induces the production and release of matrix metalloproteinases in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Recombinant human BSG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Basigin isoform 2, OK, Ok blood group, Extracellular matrix metalloproteinase inducer, Tumor cell-derived collagenase stimulatory factor, TCSF, Collagenase stimulatory factor, Hepatoma-associated antigen, HAb18G, Leukocyte activation antigen M6, EMMPRIN, CD147, EMPRIN, 5F7

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gabison EE., et al, (2005) Biochimie 87:361-368.;; Hanna SM., et al, (2003) BMC Biochem 4:17-25.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

47.5 kDa (428aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPAAGTVFT TVEDLGSKIL LTCSLNDSAT EVTGHRWLKG GVVLKEDALP GQKTEFKVDS DDQWGEYSCV FLPEPMGTAN IQLHGPPRVK AVKSSEHINE GETAMLVCKS ESVPPVTDWA WYKITDSEDK ALMNGSESRF FVSSSQGRSE LHIENLNMEA DPGQYRCNGT SSKGSDQAII TLRVRSHLAL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P35613

Internal Search Terms :

BSG, Basigin isoform 2, BSG, 5F7, CD147, EMMPRIN, OK, TCSF,ATGP3737-10ug,ATGP3737-20ug,ATGP3737-50ug,ATGP3737-100ug,ATGP3737-250ug,ATGP3737-500ug,ATGP3737-1mg,ATGP3737-10,ATGP3737-20,ATGP3737-50,ATGP3737-100,ATGP3737-250,ATGP3737-500,ATGP3737-1

more info or order :

NKMAX product webpage