Recombinant human TGF-beta RI/ALK-5 protein | NKMAX ATGP3735 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TGF-beta RI/ALK-5 protein

catalog :

ATGP3735

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TGF-beta RI/ALK-5 protein

Domain :

27-126aa

Catalog number (SKU) :

ATGP3735

NCBI :

NP_004603.1

Description :

TGFBR1, also known as TGF-beta receptor type-1 isoform 1, is a single-pass type 1 membrane protein which belongs to the protein kinase superfamily and TGFB receptor subfamily. This protein is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. Also, it plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Defects in TGFBR1 are the cause of Loeys-Dietz syndrome type 1A (LDS1A), Loeys-Diets syndrome type 2A (LDS2A), and aortic aneurysm familial thoracic type 5 (AAT5). Recombinant human TGFBR1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

TGF-beta receptor type-1 isoform 1, TGFBR1, AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TGFR-1

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wrana JL., et al, (1992) Cell 71:1003-1014.;; Huse M., et al, (1999) Cell 96:425-436.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

38kDa (342aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

LLPGATA LQCFCHLCTK DNFTCVTDGL CFVSVTETTD KVIHNSMCIA EIDLIPRDRP FVCAPSSKTG SVTTTYCCNQ DHCNKIELPT TVKSSPGLGP VEL

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P36897

Internal Search Terms :

TGF-b RI, ALK5, TGF-beta receptor type-1 isoform 1, TGFBR1, AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TGFR-1,ATGP3735-10ug,ATGP3735-20ug,ATGP3735-50ug,ATGP3735-100ug,ATGP3735-250ug,ATGP3735-500ug,ATGP3735-1mg,ATGP3735-10,ATGP3735-20,ATGP3735-50,ATGP3735-100,ATGP3735-250,ATGP3735-500,ATGP3735-1

more info or order :

NKMAX product webpage