Recombinant human Chromogranin A/CHGA protein | NKMAX ATGP3728 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Chromogranin A/CHGA protein

catalog :

ATGP3728

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Chromogranin A/CHGA protein

Domain :

19-457aa

Catalog number (SKU) :

ATGP3728

NCBI :

NP_001266.1

Description :

CHGA, also known as chromogranin-A isoform 1 preproprotein, is a member of neuroendocrine secretory proteins of the chromogranin / secretogranin family. It is a precursor of several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. This peptide negatively regulates the neuroendocrine function of autocrine or nearby cells (paracrine). This protein induces and promotes the production of secretory granules containing insulin in pancreatic islet beta cells. Recombinant human CHGA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cga, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin-2, EA-92, ES-43, Pancreastatin, parastatin, PHE5, PHES, SS-18, WA-8, WE-14, LF-19, Catestatin 2, SL21, AL-11, GV-19, GR-44, ER-37, GE-25, Serpinin-RRG, Serpinin, p-Glu serpinin precursor

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Nikoopour E., et al. (2011) J Immunol. 186:3831-3835.;; Stadinski BD., et al. (2010) Nat Immunol. 11:225-231.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

50kDa (448aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

LPVNSPM NKGDTEVMKC IVEVISDTLS KPSPMPVSQE CFETLRGDER ILSILRHQNL LKELQDLALQ GAKERAHQQK KHSGFEDELS EVLENQSSQA ELKEAVEEPS SKDVMEKRED SKEAEKSGEA TDGARPQALP EPMQESKAEG NNQAPGEEEE EEEEATNTHP PASLPSQKYP GPQAEGDSEG LSQGLVDREK GLSAEPGWQA KREEEEEEEE EAEAGEEAVP EEEGPTVVLN PHPSLGYKEI RKGESRSEAL AVDGAGKPGA EEAQDPEGKG EQEHSQQKEE EEEMAVVPQG LFRGGKSGEL EQEEERLSKE WEDSKRWSKM DQLAKELTAE KRLEGQEEEE DNRDSSMKLS FRARAYGFRG PGPQLRRGWR PSSREDSLEA GLPLQVRGYP EEKKEEEGSA NRRPEDQELE SLSAIEAELE KVAHQLQALR RG

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P10645

Internal Search Terms :

Vasostatin2, Vasostatin 2, Vasostatin, SP-I, SPI, SP-1, SP1, SP I, SP 1, Pituitary secretory protein I, Parathyroid secretory protein 1, Parastatin, Pancreastatin, Chromogranin-A isoform 1, Chromogranin-A, ChromograninA, Chromogranin A precursor, Chromogranin A parathyroid secretory protein 1, Chromogranin A isoform 1, Chromogranin A, CHGA, CHG A, CGA, beta Granin, Chromogranin-A precursor, Chromogranin-A parathyroid secretory protein 1, ATGP3728-10ug, ATGP3728-20ug, ATGP3728-50ug, ATGP3728-100ug, ATGP3728-250ug, ATGP3728-500ug, ATGP3728-1mg, ATGP3728-010, ATGP3728-020, ATGP3728-050, ATGP3728-100, ATGP3728-250, ATGP3728-500, ATGP3728-01M

more info or order :

NKMAX product webpage