Recombinant human PDGF R beta protein | NKMAX ATGP3721 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PDGF R beta protein

catalog :

ATGP3721

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PDGF R beta protein

Domain :

33-532aa

Catalog number (SKU) :

ATGP3721

NCBI :

NP_002600

Description :

PDGFRB, also known as platelet-derived growth factor receptor beta, is a member of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, SCF and Flt3-ligand. It plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. It promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. It phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Recombinant human PDGFRB, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Platelet-derived growth factor receptor beta, PDGFRB, CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kelly JD., et al. (1991) J Biol Chem. 266:8987-8992.;; Kashishian A., et al. (1992) EMBO J. 11:1373-1382.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

83.3 kDa (739aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

LVVTPPGPEL VLNVSSTFVL TCSGSAPVVW ERMSQEPPQE MAKAQDGTFS SVLTLTNLTG LDTGEYFCTH NDSRGLETDE RKRLYIFVPD PTVGFLPNDA EELFIFLTEI TEITIPCRVT DPQLVVTLHE KKGDVALPVP YDHQRGFSGI FEDRSYICKT TIGDREVDSD AYYVYRLQVS SINVSVNAVQ TVVRQGENIT LMCIVIGNEV VNFEWTYPRK ESGRLVEPVT DFLLDMPYHI RSILHIPSAE LEDSGTYTCN VTESVNDHQD EKAINITVVE SGYVRLLGEV GTLQFAELHR SRTLQVVFEA YPPPTVLWFK DNRTLGDSSA GEIALSTRNV SETRYVSELT LVRVKVAEAG HYTMRAFHED AEVQLSFQLQ INVPVRVLEL SESHPDSGEQ TVRCRGRGMP QPNIIWSACR DLKRCPRELP PTLLGNSSEE ESQLETNVTY WEEEQEFEVV STLRLQHVDR PLSVRCTLRN AVGQDTQEVI VVPHSLPFKV

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Leu33

Product Type Name :

Recombinant Protein

UniProt No. :

P09619

Internal Search Terms :

PDGF R b, Platelet-derived growth factor receptor beta, PDGFRB, CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT,ATGP3721-10ug,ATGP3721-20ug,ATGP3721-50ug,ATGP3721-100ug,ATGP3721-250ug,ATGP3721-500ug,ATGP3721-1mg,ATGP3721-10,ATGP3721-20,ATGP3721-50,ATGP3721-100,ATGP3721-250,ATGP3721-500,ATGP3721-1

more info or order :

NKMAX product webpage