Recombinant human IL-18 R beta/IL-1 R7 protein | NKMAX ATGP3719 product information

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product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-18 R beta/IL-1 R7 protein

catalog :

ATGP3719

quantity :

50 ug

price :

960 USD

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-18 R beta/IL-1 R7 protein

Domain :

20-356aa

Catalog number (SKU) :

ATGP3719

NCBI :

NP_003844.1

Description :

IL18RAP, also known as interleukin-18 receptor accessory protein, is a member of the IL-1 family of cytokines that has multiple immunoregulatory functions. It does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity and atopic asthma. Recombinant human IL18RAP protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-18 receptor accessory protein, IL18RAP, ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cheung H., et al, (2005) J Immunol. 174:5351-5357.;; Chandrasekar B., et al, (2003) Biochem Biophys Res Commun. 303:1152-1158.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

65.4 kDa (576aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioassay Procedure :

FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKR

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Phe20

Product Type Name :

Recombinant Protein

UniProt No. :

O95256

Internal Search Terms :

IL18 R b, IL1 R7, Interleukin-18 receptor accessory protein, IL18RAP, ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB,ATGP3719-10ug,ATGP3719-20ug,ATGP3719-50ug,ATGP3719-100ug,ATGP3719-250ug,ATGP3719-500ug,ATGP3719-1mg,ATGP3719-10,ATGP3719-20,ATGP3719-50,ATGP3719-100,ATGP3719-250,ATGP3719-500,ATGP3719-1

Size 2 :

50 ug

List Price 2 (USD) :

960 USD