product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human BTLA protein
catalog :
ATGP3717
quantity :
10 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human BTLA protein
Domain :
31-157aa
Catalog number (SKU) :
ATGP3717
NCBI :
NP_861445.3
Description :
BTLA, also known as B- and T-lymphocyte attenuator isoform 1, is an inhibitory molecule which belongs to the Ig superfamily. It is a type 1 transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. This protein is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1). Also, it is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses. Recombinant human BTLA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
B- and T-lymphocyte attenuator isoform 1, BTLA, BTLA1, CD272
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Watanabe N., et al, (2003) Nat. Immunol. 4:670-679. ;; Gavrieli M., et al, (2003) Biochem. Biophys. Res. Commun. 312:1236-1243.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
15.7 kDa (136aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
KESCDVQ LYIKRQSEHS ILAGDPFELE CPVKYCANRP HVTWCKLNGT TCVKLEDRQT SWKEEKNISF FILHFEPVLP NDNGSYRCSA NFQSNLIESH STTLYVTDVK SASERPSKDE MASRPWLLYS
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
Q7Z6A9
Internal Search Terms :
BTLA, B- and T-lymphocyte attenuator isoform 1, BTLA, BTLA1, CD272,ATGP3717-10ug,ATGP3717-20ug,ATGP3717-50ug,ATGP3717-100ug,ATGP3717-250ug,ATGP3717-500ug,ATGP3717-1mg,ATGP3717-10,ATGP3717-20,ATGP3717-50,ATGP3717-100,ATGP3717-250,ATGP3717-500,ATGP3717-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.