product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CD146/MCAM protein
catalog :
ATGP3715
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CD146/MCAM protein
Domain :
24-559aa
Catalog number (SKU) :
ATGP3715
NCBI :
NP_006491
Description :
MCAM, also known as cell surface glycoprotein MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. It is associated with various carcinomas such as tumor progression, metastasis and may be involved in embryonic neural development. This protein also plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Recombinant human MCAM protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Melanoma cell adhesion molecule, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma-associated antigen A32, Gicerin, Melanoma-associated antigen MUC18, MUC18, S-endo 1 endothelial-associated antigen, CD146, MelCAM, METCAM, HEMCAM
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Dagur PK., et al, (2014) Clin Immunol. 152:36-47.;; Wragg JW., et al, (2016) Cancer Res. 76:2314-2326.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
61kDa (547aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
VPGEAEQPAP ELVEVEVGST ALLKCGLSQS QGNLSHVDWF SVHKEKRTLI FRVRQGQGQS EPGEYEQRLS LQDRGATLAL TQVTPQDERI FLCQGKRPRS QEYRIQLRVY KAPEEPNIQV NPLGIPVNSK EPEEVATCVG RNGYPIPQVI WYKNGRPLKE EKNRVHIQSS QTVESSGLYT LQSILKAQLV KEDKDAQFYC ELNYRLPSGN HMKESREVTV PVFYPTEKVW LEVEPVGMLK EGDRVEIRCL ADGNPPPHFS ISKQNPSTRE AEEETTNDNG VLVLEPARKE HSGRYECQGL DLDTMISLLS EPQELLVNYV SDVRVSPAAP ERQEGSSLTL TCEAESSQDL EFQWLREETG QVLERGPVLQ LHDLKREAGG GYRCVASVPS IPGLNRTQLV NVAIFGPPWM AFKERKVWVK ENMVLNLSCE ASGHPRPTIS WNVNGTASEQ DQDPQRVLST LNVLVTPELL ETGVECTASN DLGKNTSILF LELVNLTTLT PDSNTTTGLS TSTASPHTRA NSTSTERKLP EPESRGAAAL EHHHHHH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Val24
Product Type Name :
Recombinant Protein
UniProt No. :
P43121
Internal Search Terms :
MCAM, Cell surface glycoprotein MUC18, MCAM, CD146, MUC18,ATGP3715-10ug,ATGP3715-20ug,ATGP3715-50ug,ATGP3715-100ug,ATGP3715-250ug,ATGP3715-500ug,ATGP3715-1mg,ATGP3715-10,ATGP3715-20,ATGP3715-50,ATGP3715-100,ATGP3715-250,ATGP3715-500,ATGP3715-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.