product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant rat IL-6 protein
catalog :
ATGP3711
quantity :
5 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant rat IL-6 protein
Domain :
25-211aa
Catalog number (SKU) :
ATGP3711
NCBI :
NP_036721
Description :
Il6, also known as interleukin 6, is an alpha-helical phosphorylated and glycosylated cytokine. This protein is important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism and cancer progression. Also, it can function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise In addition, it enhances hematopoietic stem cell proliferation and the differentiation of Th17 cells, memory B cells, and plasma cells. Recombinant rat Il6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Interleukin 6, Il6, Ifnb2, ILg6, Interferon beta 2
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Garbers C., et al, (2012) Cytokine Growth Factor Rev. 23:85-97.;; Northemann W., et al, (1989) J. Biol. Chem. 264:16072-16082.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range ≤0.1ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Rat
Gene Category :
Hormones & Cytokines
Molecular Weight :
22.8 kDa (196aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range ≤0.1 ng/ml.
Amino Acid Sequence :
FPTSQVR RGDFTEDTTH NRPVYTTSQV GGLITYVLRE ILEMRKELCN GNSDCMNSDDALSENNLKLP EIQRNDGCFQ TGYNQEICLL KICSGLLEFR FYLEFVKNNL QDNKKDKARVIQSNTETLVH IFKQEIKDSY KIVLPTPTSN ALLMEKLESQ KEWLRTKTIQ LILKALEEFL KVTMRSTRQT
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P20607
Internal Search Terms :
IL6,ATGP3711-10ug,ATGP3711-20ug,ATGP3711-50ug,ATGP3711-100ug,ATGP3711-250ug,ATGP3711-500ug,ATGP3711-1mg,ATGP3711-10,ATGP3711-20,ATGP3711-50,ATGP3711-100,ATGP3711-250,ATGP3711-500,ATGP3711-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.