product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IL-4R alpha/IL4R protein
catalog :
ATGP3710
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IL-4R alpha/IL4R protein
Domain :
26-232aa
Catalog number (SKU) :
ATGP3710
NCBI :
NP_000409
Description :
IL4R, also known as interleukin 4 receptor subunit alpha isoform, is a pleiotropic cytokine produced by T lymphocytes. It plays an important role in immune responsiveness by regulating proliferation and differentiation of a variety of lymphoid and myeloid cells via binding to high affinity receptors. It markedly inhibits IL-1 production by highly purified normal human monocytes. It has been demonstrated to affect the growth of different human malignancies including pancreatic cancer cells. It plays an important role in Th2-biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. Recombinant human IL4R, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Interleukin 4 receptor subunit alpha isoform, IL4R, CD124, IL-4RA, IL4RA, IL-4 receptor subunit alpha; IL-4R subunit alpha
Concentration :
0.25mg/ml (determined by BCA assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Traub B., et al. (2017) Int J Mol Sci. 18.;; Idzerda RL., et al. (1990) J Exp Med. 171:861-873.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
24.7 kDa (215aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MKVLQEPTCV SDYMSISTCE WKMNGPTNCS TELRLLYQLV FLLSEAHTCI PENNGGAGCV CHLLMDDVVS ADNYTLDLWA GQQLLWKGSF KPSEHVKPRA PGNLTVHTNV SDTLLLTWSN PYPPDNYLYN HLTYAVNIWS ENDPADFRIY NVTYLEPSLR IAASTLKSGI SYRARVRAWA QCYNTTWSEW SPSTKWHNSY REPFEQH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met26
Product Type Name :
Recombinant Protein
UniProt No. :
P24394
Internal Search Terms :
IL4 R a, Interleukin 4 receptor subunit alpha isoform, IL4R, CD124, IL-4RA, IL4RA,ATGP3710-10ug,ATGP3710-20ug,ATGP3710-50ug,ATGP3710-100ug,ATGP3710-250ug,ATGP3710-500ug,ATGP3710-1mg,ATGP3710-10,ATGP3710-20,ATGP3710-50,ATGP3710-100,ATGP3710-250,ATGP3710-500,ATGP3710-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.