product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Siglec-2/CD22 protein
catalog :
ATGP3707
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Siglec-2/CD22 protein
Domain :
20-687aa
Catalog number (SKU) :
ATGP3707
NCBI :
NP_001762
Description :
CD22, also known as B-cell receptor CD22 isoform 1, is a member of the immunoglobulin (Ig) superfamily. It mediates B-cell to B-cell interactions and is involved in the localization of B-cells in lymphoid tissues. This protein plays a positive regulation through interaction with Src family tyrosine kinases and also acts as an inhibitory receptor by recruiting cytoplasmic phosphatases. Recombinant human CD22 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
B-cell receptor CD22 isoform 1, CD22, SIGLEC-2, SIGLEC2
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Yu SF., et al, (2015) Clin Cancer Res. 21:3298-3306.;; Lumb S., et al, (2016) J Cell Commun Signal. 10:143-151.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
102.1 kDa (907aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
DSSKWVFEHP ETLYAWEGAC VWIPCTYRAL DGDLESFILF HNPEYNKNTS KFDGTRLYES TKDGKVPSEQ KRVQFLGDKN KNCTLSIHPV HLNDSGQLGL RMESKTEKWM ERIHLNVSER PFPPHIQLPP EIQESQEVTL TCLLNFSCYG YPIQLQWLLE GVPMRQAAVT STSLTIKSVF TRSELKFSPQ WSHHGKIVTC QLQDADGKFL SNDTVQLNVK HTPKLEIKVT PSDAIVREGD SVTMTCEVSS SNPEYTTVSW LKDGTSLKKQ NTFTLNLREV TKDQSGKYCC QVSNDVGPGR SEEVFLQVQY APEPSTVQIL HSPAVEGSQV EFLCMSLANP LPTNYTWYHN GKEMQGRTEE KVHIPKILPW HAGTYSCVAE NILGTGQRGP GAELDVQYPP KKVTTVIQNP MPIREGDTVT LSCNYNSSNP SVTRYEWKPH GAWEEPSLGV LKIQNVGWDN TTIACAACNS WCSWASPVAL NVQYAPRDVR VRKIKPLSEI HSGNSVSLQC DFSSSHPKEV QFFWEKNGRL LGKESQLNFD SISPEDAGSY SCWVNNSIGQ TASKAWTLEV LYAPRRLRVS MSPGDQVMEG KSATLTCESD ANPPVSHYTW FDWNNQSLPY HSQKLRLEPV KVQHSGAYWC QGTNSVGKGR SPLSTLTVYY SPETIGRR
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Asp20
Product Type Name :
Recombinant Protein
UniProt No. :
P20273
Internal Search Terms :
Siglec2, CD22, B-cell receptor CD22 isoform 1, CD22, SIGLEC-2, SIGLEC2,ATGP3707-10ug,ATGP3707-20ug,ATGP3707-50ug,ATGP3707-100ug,ATGP3707-250ug,ATGP3707-500ug,ATGP3707-1mg,ATGP3707-10,ATGP3707-20,ATGP3707-50,ATGP3707-100,ATGP3707-250,ATGP3707-500,ATGP3707-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.