product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TIGIT protein
catalog :
ATGP3704
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TIGIT protein
Domain :
22-141aa
Catalog number (SKU) :
ATGP3704
NCBI :
NP_776160
Description :
TIGIT, also known as T-cell immunoreceptor with Ig and ITIM domains, is a surface protein containing and immunoglobulin variable domain. This protein is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells. Also, it binds with high affinity to the poliovirus receptor which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Recombinant human TIGIT, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
T-cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Yu X., et al, (2009) Nat. Immunol. 10:48-57.;; Godefroy E., et al, (2015) Haematologica 100:1415-1425.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
40kDa (359aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MMTGTIETTG NISAEKGGSI ILQCHLSSTT AQVTQVNWEQ QDQLLAICNA DLGWHISPSF KDRVAPGPGL GLTLQSLTVN DTGEYFCIYH TYPDGTYTGR IFLEVLESSV AEHGARFQIP
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met22
Product Type Name :
Recombinant Protein
UniProt No. :
Q495A1
Internal Search Terms :
TIGIT, T-cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM,ATGP3704-10ug,ATGP3704-20ug,ATGP3704-50ug,ATGP3704-100ug,ATGP3704-250ug,ATGP3704-500ug,ATGP3704-1mg,ATGP3704-10,ATGP3704-20,ATGP3704-50,ATGP3704-100,ATGP3704-250,ATGP3704-500,ATGP3704-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.