Recombinant human GM-CSF R alpha protein | NKMAX ATGP3697 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GM-CSF R alpha protein

catalog :

ATGP3697

quantity :

5 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GM-CSF R alpha protein

Domain :

20-320aa

Catalog number (SKU) :

ATGP3697

NCBI :

NP_001155003

Description :

CSF2RA, also known as granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g, is a well-known hemopoietic growth factor that is used in the clinic to correct neutropaenia, usually as a result of chemotherapy. It is a key regulatory molecule causative of this aortopathy, and modulation of this cytokine might be an exploitable treatment strategy for the condition. It transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Recombinant human CSF2RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g, CSF2RA, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, alphaGMR

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Van Nieuwenhuijze A., et al. (2013) Mol Immunol. 56:675-682.;; Raines MA., et al. (1991) Proc Natl Acad Sci U S A. 88:8203-8207.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its ability to inhibit proliferation using TF-1 human erythroleukemic cells. The ED50 range ≤10ug/ml with Human GM-CSF.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

35.9 kDa (310aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Measured by its ability to inhibit proliferation using TF-1 human erythroleukemic cells. The ED50 range ≤10 ug/ml with Human GM-CSF.

Amino Acid Sequence :

LIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDG

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P15509

Internal Search Terms :

GM-CSF R a,ATGP3697-10ug,ATGP3697-20ug,ATGP3697-50ug,ATGP3697-100ug,ATGP3697-250ug,ATGP3697-500ug,ATGP3697-1mg,ATGP3697-10,ATGP3697-20,ATGP3697-50,ATGP3697-100,ATGP3697-250,ATGP3697-500,ATGP3697-1

more info or order :

NKMAX product webpage