Recombinant human CD58/LFA-3 protein | NKMAX ATGP3693 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD58/LFA-3 protein

catalog :

ATGP3693

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD58/LFA-3 protein

Domain :

29-215aa

Catalog number (SKU) :

ATGP3693

NCBI :

NP_001770

Description :

CD58, also known as lymphocyte function-associated antigen 3 isoform 1, is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. It is an important regulator of immune cell function which occurs as both surface-associated and soluble forms. It is associated with increased risk for multiple sclerosis. Recombinant human CD58, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Lymphocyte function-associated antigen 3 isoform 1, CD58, ag3, LFA-3, LFA3

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Abdul Razak FR., et al. (2016) Genes Immun. 17:363-366.;; Kirby AC., et al. (2000) Cell Adhes Commun. 7:453-464.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

22.5 kDa (196aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR HHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P19256

Internal Search Terms :

CD58, LFA3, Lymphocyte function-associated antigen 3 isoform 1, CD58, ag3, LFA-3, LFA3,ATGP3693-10ug,ATGP3693-20ug,ATGP3693-50ug,ATGP3693-100ug,ATGP3693-250ug,ATGP3693-500ug,ATGP3693-1mg,ATGP3693-10,ATGP3693-20,ATGP3693-50,ATGP3693-100,ATGP3693-250,ATGP3693-500,ATGP3693-1

more info or order :

NKMAX product webpage