Recombinant human Epigen protein | NKMAX ATGP3682 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Epigen protein

catalog :

ATGP3682

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Epigen protein

Domain :

23-110aa

Catalog number (SKU) :

ATGP3682

NCBI :

NP_001257918

Description :

EPGN, also known as epigen isoform 1, is a novel member of the epidermal growth factor superfamily. It is the last ligand of ErbB receptors and reveals intricate relationships between affinity and mitogenicity. It stimulated the proliferation of HaCaT cells, and this proliferation was blocked by an antibody to the extracellular domain of the receptor tyrosine kinase c-erbB-1. It also may constitute a novel molecular target for wound-healing therapy with its ability to promote the growth of epithelial cells. It has been reported to have high mitogenic activity but low affinity for its receptor. It has been reported in cancer specimens of the breast, bladder, and prostate. Recombinant human EPGN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Epigen isoform 1, EPGN, ALGV3072, EPG, PRO9904

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kochupurakkal BS., et al. (2005) J Biol Chem. 280:8503-8512.;; Strachan L., et al. (2001) J Biol Chem. 276:18265-18271.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

10.8 kDa (97aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE KHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q6UW88

Internal Search Terms :

Epigen, Epigen isoform 1, EPGN, ALGV3072, EPG, PRO9904,ATGP3682-10ug,ATGP3682-20ug,ATGP3682-50ug,ATGP3682-100ug,ATGP3682-250ug,ATGP3682-500ug,ATGP3682-1mg,ATGP3682-10,ATGP3682-20,ATGP3682-50,ATGP3682-100,ATGP3682-250,ATGP3682-500,ATGP3682-1

more info or order :

NKMAX product webpage