Recombinant human CD161/KLRB1 protein | NKMAX ATGP3675 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD161/KLRB1 protein

catalog :

ATGP3675

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD161/KLRB1 protein

Domain :

67-225aa

Catalog number (SKU) :

ATGP3675

NCBI :

NP_002249.1

Description :

KLRB1, also known as killer cell lectin-like receptor subfamily B member 1, is classified as a type II membrane protein because it has an external C terminus. It is expressed by NK cells and may be involved in the regulation of NK cell function. It plays a novel and important role in B cell maturation within the GC in humans. It is expressed by lymphocytes found in human gut and liver, as well as blood, especially natural killer (NK) cells, T helper 17 (Th17) cells, and a population of unconventional T cells known as mucosal-associated invariant T (MAIT) cells. It is also expressed, at intermediate levels, on a prominent subset of polyclonal CD8+ T cells, including antiviral populations that display a memory phenotype. Recombinant human KLRB1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Killer cell lectin like receptor B1, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, HNKR-P1a, NKR-P1A, Natural killer cell surface protein P1A, CD161, CLEC5B, NKRP1A, NKR-P1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Fergusson JR., et al. (2016) Mucosal Immunol. 9:401-413.;; Llibre A1., et al. (2016) J Immunol. 196:2085-2094.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

45.7 kDa (401aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QKSSIEK CSVDIQQSRN KTTERPGLLN CPIYWQQLRE KCLLFSHTVN PWNNSLADCS TKESSLLLIR DKDELIHTQN LIRDKAILFW IGLNFSLSEK NWKWINGSFL NSNDLEIRGD AKENSCISIS QTSVYSEYCS TEIRWICQKE LTPVRNKVYP DS

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q12918

Internal Search Terms :

CD161, Killer cell lectin-like receptor subfamily B member 1, KLRB1, CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A, NKRP1A,ATGP3675-10ug,ATGP3675-20ug,ATGP3675-50ug,ATGP3675-100ug,ATGP3675-250ug,ATGP3675-500ug,ATGP3675-1mg,ATGP3675-10,ATGP3675-20,ATGP3675-50,ATGP3675-100,ATGP3675-250,ATGP3675-500,ATGP3675-1

more info or order :

NKMAX product webpage