product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CD16b/FCGR3B protein
catalog :
ATGP3673
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CD16b/FCGR3B protein
Domain :
21-200aa
Catalog number (SKU) :
ATGP3673
NCBI :
NP_000561.3
Description :
FCGR3B, also known as low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, is a member of Ig super family. It encodes a glycosylphosphatidylinositol (GPI) -anchored protein that is expressed constitutively by neutrophils and after gamma-interferon stimulation by eosinophils. This protein binds to complex or aggregated IgG and monomeric IgG. Unlike III-A, it cannot mediate antibody-dependent cytotoxicity and phagocytosis. It can be a trap of immune complexes in peripheral blood circulation that does not activate neutrophils. Recombinant human FCGR3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, IgG Fc receptor III-1, IGFR3, FCRIIIb, FCRIII, FCR-10, FCGR3B, FCGR3, FcgammaRIIIb, Fc-gamma RIII-beta, FCG3, Fc gamma receptor IIIb, Fc fragment of IgG receptor IIIb, CD16-I, CD16b, CD16
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ravetch J.V., et al. (2001) Annu. Rev. Immunol. 19:275-290.;; Machado LR., et al. (2012) Am. J. Hum. Genet. 90:973-985.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
21.4 kDa (188aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
EDLPKAVVFL EPQWYSVLEK DSVTLKCQGA YSPEDNSTQW FHNENLISSQ ASSYFIDAAT VNDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKDRKY FHHNSDFHIP KATLKDSGSY FCRGLVGSKN VSSETVNITI TQGLAVSTIS
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Glu21
Product Type Name :
Recombinant Protein
UniProt No. :
O75015
Internal Search Terms :
Fc g RIIIB, CD16b, Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, FCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb,ATGP3673-10ug,ATGP3673-20ug,ATGP3673-50ug,ATGP3673-100ug,ATGP3673-250ug,ATGP3673-500ug,ATGP3673-1mg,ATGP3673-10,ATGP3673-20,ATGP3673-50,ATGP3673-100,ATGP3673-250,ATGP3673-500,ATGP3673-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.