Recombinant human CD117/c-kit protein | NKMAX ATGP3665 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD117/c-kit protein

catalog :

ATGP3665

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD117/c-kit protein

Domain :

26-524aa

Catalog number (SKU) :

ATGP3665

NCBI :

NP_000213.1

Description :

KIT, also known as mast/stem cell growth factor receptor Kit isoform 1, is a cytokine receptor that is expressed not only in hematopoietic stem cells but also in other cell types. It binds to receptor tyrosine kinase type III, a stem cell factor, also called a rigid factor or c-kit ligand. When this receptor binds to stem cell factor (SCF), it forms a dimer that activates intrinsic tyrosine kinase activity, which, in turn, phosphorylates and activates signaling molecules that propagate signals in cells. This receptor protects vascular smooth muscle cells from apoptosis and helps restore cardiac function after myocardial infarction. Recombinant human KIT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Mast/stem cell growth factor receptor Kit isoform 1, KIT, C-Kit, CD117, PBT, SCFR

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yarden Y., et al. (1987) EMBO J. 6:3341-3451.;; Anzai N., et al. (2002) Blood. 99:4413-4421.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

57.1 kDa (507aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QPSVSPGEPS PPSIHPGKSD LIVRVGDEIR LLCTDPGFVK WTFEILDETN ENKQNEWITE KAEATNTGKY TCTNKHGLSN SIYVFVRDPA KLFLVDRSLY GKEDNDTLVR CPLTDPEVTN YSLKGCQGKP LPKDLRFIPD PKAGIMIKSV KRAYHRLCLH CSVDQEGKSV LSEKFILKVR PAFKAVPVVS VSKASYLLRE GEEFTVTCTI KDVSSSVYST WKRENSQTKL QEKYNSWHHG DFNYERQATL TISSARVNDS GVFMCYANNT FGSANVTTTL EVVDKGFINI FPMINTTVFV NDGENVDLIV EYEAFPKPEH QQWIYMNRTF TDKWEDYPKS ENESNIRYVS ELHLTRLKGT EGGTYTFLVS NSDVNAAIAF NVYVNTKPEI LTYDRLVNGM LQCVAAGFPE PTIDWYFCPG TEQRCSASVL PVDVQTLNSS GPPFGKLVVQ SSIDSSAFKH NGTVECKAYN DVGKTSAYFN FAFKGNNKEQ IHPHTLFTP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln26

Product Type Name :

Recombinant Protein

UniProt No. :

P10721

Internal Search Terms :

CD117, c-kit, Mast/stem cell growth factor receptor Kit isoform 1, KIT, C-Kit, CD117, PBT, SCFR,ATGP3665-10ug,ATGP3665-20ug,ATGP3665-50ug,ATGP3665-100ug,ATGP3665-250ug,ATGP3665-500ug,ATGP3665-1mg,ATGP3665-10,ATGP3665-20,ATGP3665-50,ATGP3665-100,ATGP3665-250,ATGP3665-500,ATGP3665-1

more info or order :

NKMAX product webpage