product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human B7-1/CD80 protein
catalog :
ATGP3663
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human B7-1/CD80 protein
Domain :
35-242aa
Catalog number (SKU) :
ATGP3663
NCBI :
NP_005182
Description :
CD80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily. This protein can bind to either human or mouse CD28 and CTLA-4. It is expressed on activated B cells, activated T cells, and macrophages. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. Therefore, it is considered a promising therapeutic target for autoimmune diseases and various carcinomas. Recombinant human CD80, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Activation B7-1 antigen, B7, B7.1, B7-1, BB1, CD28LG, CD28LG1, CD80, CTLA-4 counter-receptor B7.1, FcalphaRI, LAB7, T-lymphocyte activation antigen CD80
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Zang X., et al. (2007) Clin Cancer Res. 13:5271-5279.;; Kakoulidou M., et al. (2007) Scand. J. Immunol. 66:529-537.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human CD28 (CAT# ATGP3603)
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
24.9 kDa (216aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Human CD80 is coated at 1ug/ml (100 ul/well) can bind CD28 (CAT# ATGP3603) in a Functional ELISA assay.
Amino Acid Sequence :
VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKD AFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSF MCLIKYGHLR VNQTFNWNTT KQEHFPDN
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Val35
Product Type Name :
Recombinant Protein
UniProt No. :
P33681
Internal Search Terms :
B71, CD80, T-lymphocyte activation antigen CD80, CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7,ATGP3663-10ug,ATGP3663-20ug,ATGP3663-50ug,ATGP3663-100ug,ATGP3663-250ug,ATGP3663-500ug,ATGP3663-1mg,ATGP3663-10,ATGP3663-20,ATGP3663-50,ATGP3663-100,ATGP3663-250,ATGP3663-500,ATGP3663-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.