product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CD89/FCAR protein
catalog :
ATGP3660
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CD89/FCAR protein
Domain :
22-227aa
Catalog number (SKU) :
ATGP3660
NCBI :
NP_001991
Description :
FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. Recombinant human FCAR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
CD89, CTB-61M7.2, Fc alpha receptor, Fc fragment of IgA receptor, FcalphaR, FcalphaRI, FCAR, IgA Fc receptor, Immunoglobulin alpha Fc receptor isoform
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Maliszewski, C. R., et al. (1990) J. Exp. Med. 172:1665-1672.;; Kanamaru, Y., et al. (2007) Blood. 109:203-211.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
24.5 kDa (215aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P24071
Internal Search Terms :
FCAR, CD89, Immunoglobulin alpha Fc receptor isoform, FCAR, CD89, CTB-61M7.2, FcalphaRI,ATGP3660-10ug,ATGP3660-20ug,ATGP3660-50ug,ATGP3660-100ug,ATGP3660-250ug,ATGP3660-500ug,ATGP3660-1mg,ATGP3660-10,ATGP3660-20,ATGP3660-50,ATGP3660-100,ATGP3660-250,ATGP3660-500,ATGP3660-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.