Recombinant human ULBP-4/RAET1E protein | NKMAX ATGP3656 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ULBP-4/RAET1E protein

catalog :

ATGP3656

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ULBP-4/RAET1E protein

Domain :

31-225aa

Catalog number (SKU) :

ATGP3656

NCBI :

NP_631904

Description :

RAET1E, also known as NKG2D ligand 4 isoform 1, is a member of the RAET1/ULBP family of cell surface protein that function as ligands for NKG2D. This protein is abnormally expressed on most colon cancer and some other tumor cell lines and virus infected peripheral blood cells. It binds and co-stimulates NKG2D expressing effector cells including NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells, activating cytolytic activity and/or cytokine production. Also, it functions as a stress-induced ligand for NKG2D receptor. Recombinant human RAET1E, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Retinoic acid early transcript 1E, Lymphocyte effector toxicity activation ligand, NKG2D ligand 4, N2DL-4, NKG2DL4, RAE-1-like transcript 4, UL16-binding protein 4, LETAL, N2DL4, ULBP4

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chalupny NJ., et al, (2003) Biochem. Biophys. Res. Commun. 305:129-135.;; Kong Y., et al, (2009) Blood 114:310-317.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

49.6 kDa (437aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q8TD07

Internal Search Terms :

ULBP4, RAET1E, NKG2D ligand 4 isoform 1, RAET1E, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4,ATGP3656-10ug,ATGP3656-20ug,ATGP3656-50ug,ATGP3656-100ug,ATGP3656-250ug,ATGP3656-500ug,ATGP3656-1mg,ATGP3656-10,ATGP3656-20,ATGP3656-50,ATGP3656-100,ATGP3656-250,ATGP3656-500,ATGP3656-1

more info or order :

NKMAX product webpage