Recombinant human FGF receptor 3/FGFR3 protein | NKMAX ATGP3654 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FGF receptor 3/FGFR3 protein

catalog :

ATGP3654

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FGF receptor 3/FGFR3 protein

Domain :

23-375aa

Catalog number (SKU) :

ATGP3654

NCBI :

NP_000133

Description :

FGFR3, also known as fibroblast growth factor receptor 3 isoform 1, is a member of the fibroblast growth factor receptor family. It is a family of polypeptide growth factors involved in a variety of activities including mitogenesis, angiogenesis, and wound healing. Its activation results in autophosphorylation of multiple tyrosine residues within the intracellular domain. It plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. It frequently involved in human developmental disorders and is associated with several cancers, including multiple myeloma (MM). Recombinant human FGFR3, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Fibroblast growth factor receptor 3 isoform 1, FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4, Achondroplasia, Thanatophoric dwarfism

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Keegan K., et al. (1991) Proc Natl Acad Sci U S A. 88:1095-1099.;; Castano-Betancourt MC., et al. (2016) PLoS Genet. 12:e1006260.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

65.1 kDa (592aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ESLGTEQRVV GRAAEVPGPE PGQQEQLVFG SGDAVELSCP PPGGGPMGPT VWVKDGTGLV PSERVLVGPQ RLQVLNASHE DSGAYSCRQR LTQRVLCHFS VRVTDAPSSG DDEDGEDEAE DTGVDTGAPY WTRPERMDKK LLAVPAANTV RFRCPAAGNP TPSISWLKNG REFRGEHRIG GIKLRHQQWS LVMESVVPSD RGNYTCVVEN KFGSIRQTYT LDVLERSPHR PILQAGLPAN QTAVLGSDVE FHCKVYSDAQ PHIQWLKHVE VNGSKVGPDG TPYVTVLKTA GANTTDKELE VLSLHNVTFE DAGEYTCLAG NSIGFSHHSA WLVVLPAEEE LVEADEAGSV YAGLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Glu23

Product Type Name :

Recombinant Protein

UniProt No. :

P22607

Internal Search Terms :

FGF R3, Fibroblast growth factor receptor 3 isoform 1, FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4,ATGP3654-10ug,ATGP3654-20ug,ATGP3654-50ug,ATGP3654-100ug,ATGP3654-250ug,ATGP3654-500ug,ATGP3654-1mg,ATGP3654-10,ATGP3654-20,ATGP3654-50,ATGP3654-100,ATGP3654-250,ATGP3654-500,ATGP3654-1

more info or order :

NKMAX product webpage