product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Sepiapterin reductase/SPR protein
catalog :
ATGP3652
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Sepiapterin reductase/SPR protein
Domain :
1-262aa
Catalog number (SKU) :
ATGP3652
NCBI :
NP_035597
Description :
Spr also known as Sepiapterin reductase, belongs to the Short-chain dehydrogenase/reductase (Sdr) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. Spr is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in Spr cause DOPA-responsive dystonia defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Recombinant mouse Spr protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Sepiapterin reductase, AA409688, Gm10328
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 1mM DTT, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Tobin JE., et al. (2007). Brain Res. 30;;1139:42-7.;; Ohye T., et al. (1998). Biochem Biophys Res Commun. 251(2):597-602.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Redox Proteins
Molecular Weight :
30.3 kDa (285aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMEAGGLG CAVCVLTGAS RGFGRALAPQ LARLLSPGSV MLVSARSESM LRQLKEELGA QQPDLKVVLA AADLGTEAGV QRLLSAVREL PRPEGLQRLL LINNAATLGD VSKGFLNVND LAEVNNYWAL NLTSMLCLTS GTLNAFQDSP GLSKTVVNIS SLCALQPYKG WGLYCAGKAA RDMLYQVLAA EEPSVRVLSY APGPLDNDMQ QLARETSKDP ELRSKLQKLK SDGALVDCGT SAQKLLGLLQ KDTFQSGAHV DFYDC
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q91XH5
Internal Search Terms :
Spr, Sepiapterin reductase, AA409688, Gm10328,ATGP3652-10ug,ATGP3652-20ug,ATGP3652-50ug,ATGP3652-100ug,ATGP3652-250ug,ATGP3652-500ug,ATGP3652-1mg,ATGP3652-10,ATGP3652-20,ATGP3652-50,ATGP3652-100,ATGP3652-250,ATGP3652-500,ATGP3652-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.