product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Adenosylhomocysteinase/AHCY protein
catalog :
ATGP3650
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Adenosylhomocysteinase/AHCY protein
Domain :
1-432aa
Catalog number (SKU) :
ATGP3650
NCBI :
NP_057870
Description :
Ahcy, also known as Adenosylhomocysteinase, is an enzyme that catalyzes the reversible hydrolysis of S-sdenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AdoHcy hydrolysis is a reversible reaction with an equilibrium favoring AdoHcy formation, but hydrolysis prevails under physiological conditions due to the rapid removal of adenosine and homocysteine. Thus, AHCY s activity in mammals is directly related to homocysteine level, an independent risk factor for vascular disease. It also functions as a regulator of biological transmethylation by controlling the concentration of AdoHcy, a potent competitive inhibitor of all S-adenosyl-L-methionine methyltransferases. Recombinant mouse Ahcy, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
S-adenosylhomocysteine hydrolase, AdoHcyase, CUBP, Liver copper-binding protein, S-adenosyl-L-homocysteine hydrolase, SAHH
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Vugrek O., et al. (2009) Hum Mutat. 30(4): E555-65.;; Park SJ. et al., (2015) Am J Cancer Res. 5(7):2127-2138
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Enzymes & Proteases
Molecular Weight :
50.2 kDa (456aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MSDKLP YKVADIGLAA WGRKALDIAE NEMPGLMRMR EMYSASKPLK GARIAGCLHM TVETAVLIET LVALGAEVRW SSCNIFSTQD HAAAAIAKAG IPVFAWKGET DEEYLWCIEQ TLHFKDGPLN MILDDGGDLT NLIHTKYPQL LSGIRGISEE TTTGVHNLYK MMSNGILKVP AINVNDSVTK SKFDNLYGCR ESLIDGIKRA TDVMIAGKVA VVAGYGDVGK GCAQALRGFG ARVIITEIDP INALQAAMEG YEVTTMDEAC KEGNIFVTTT GCVDIILGRH FEQMKDDAIV CNIGHFDVEI DVKWLNENAV EKVNIKPQVD RYWLKNGRRI ILLAEGRLVN LGCAMGHPSF VMSNSFTNQV MAQIELWTHP DKYPVGVHFL PKKLDEAVAE AHLGKLNVKL TKLTEKQAQY LGMPINGPFK PDHYRY
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P50247
Internal Search Terms :
Ahcy, Adenosylhomocysteinase, AA987153, AL024110, CuBP, SAHH,ATGP3650-10ug,ATGP3650-20ug,ATGP3650-50ug,ATGP3650-100ug,ATGP3650-250ug,ATGP3650-500ug,ATGP3650-1mg,ATGP3650-10,ATGP3650-20,ATGP3650-50,ATGP3650-100,ATGP3650-250,ATGP3650-500,ATGP3650-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.