Recombinant human SLAMF2/CD48 protein | NKMAX ATGP3642 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SLAMF2/CD48 protein

catalog :

ATGP3642

quantity :

10 ug

price :

110 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SLAMF2/CD48 protein

Domain :

27-220aa

Catalog number (SKU) :

ATGP3642

NCBI :

NP_001769.2

Description :

CD48, also known as CD48 antigen isoform 1, is a GPI-linked protein in the CD2 family of immunoglobulin superfamily molecules. This protein is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48-CD2 interactions promote T cell activation and class switching to IgG2a in B cells. High affinity CD48-2B4 interactions can either promote or inhibit NK cell and cytotoxic T cell (CTL) activation. It expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation. Recombinant human CD48, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

B-cell membrane protein, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2, Signaling lymphocytic activation molecule 2, TCT.1

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kis-Toth K., et al, (2014) J. Immunol. 192:4436-4442.;; Fisher RC., et al, (1991) Mol. Cell. Biol. 11:1614-1623.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human CD244 (CAT# ATGP3552)

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

23.4 kDa (203aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human CD48/SLAMF2 is coated at 2 ug/ml (100 ul/well) can bind Human CD244 (CAT# ATGP3552) in a Functional ELISA assay.

Amino Acid Sequence :

QGHLVHM TVVSGSNVTL NISESLPENY KQLTWFYTFD QKIVEWDSRK SKYFESKFKG RVRLDPQSGA LYISKVQKED NSTYIMRVLK KTGNEQEWKI KLQVLDPVPK PVIKIEKIED MDDNCYLKLS CVIPGESVNY TWYGDKRPFP KELQNSVLET TLMPHNYSRC YTCQVSNSVS SKNGTVCLSP PCTLARS

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P09326

Internal Search Terms :

CD48, SLAMF2, CD48 antigen isoform 1, CD48, BCM1, BLAST, BLAST1, hCD48, mCD48, MEM-102, SLAMF2,ATGP3642-10ug,ATGP3642-20ug,ATGP3642-50ug,ATGP3642-100ug,ATGP3642-250ug,ATGP3642-500ug,ATGP3642-1mg,ATGP3642-10,ATGP3642-20,ATGP3642-50,ATGP3642-100,ATGP3642-250,ATGP3642-500,ATGP3642-1

more info or order :

NKMAX product webpage