Recombinant human CD158d/KIR2DL4 protein | NKMAX ATGP3639 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD158d/KIR2DL4 protein

catalog :

ATGP3639

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD158d/KIR2DL4 protein

Domain :

24-242aa

Catalog number (SKU) :

ATGP3639

NCBI :

NP_002246

Description :

KIR2DL4, also known as killer cell immunoglobulin-like receptor 2DL4, is a member of the killer cell Ig-like receptor (KIR) family. KIR proteins with the long cytoplasmic domain transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. This protein induces NK cells to produce IFN-gamma and stimulation with IL-2 upregulates cell surface expression on CD56dim cells and leads to the inhibition of the cytolytic NK cell function. Recombinant human KIR2DL4 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Killer cell immunoglobulin like receptor two Ig domains and long cytoplasmic tail 4, Killer cell immunoglobulin-like receptor 2DL4, CD158 antigen-like family member D, G9P, Killer cell inhibitory receptor 103AS, KIR-103AS, MHC class I NK cell receptor KIR103AS, CD158D, KIR103AS,103AS, 15.212

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Le Page ME., et al, (2014) J Immunol. 192:732-740.;; Li G., et al, (2008) J Leukoc Biol. 84:824-834.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

51kDa (458aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

HVGGQDKPFC SAWPSAVVPQ GGHVTLRCHY RRGFNIFTLY KKDGVPVPEL YNRIFWNSFL ISPVTPAHAG TYRCRGFHPH SPTEWSAPSN PLVIMVTGLY EKPSLTARPG PTVRAGENVT LSCSSQSSFD IYHLSREGEA HELRLPAVPS INGTFQADFP LGPATHGETY RCFGSFHGSP YEWSDPSDPL PVSVTGNPSS SWPSPTEPSF KTGIARHLHL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

His24

Product Type Name :

Recombinant Protein

UniProt No. :

Q99706

Internal Search Terms :

KIR2DL4, CD158d, killer cell immunoglobulin-like receptor 2DL4, KIR2DL4, CD158D, G9P, KIR-103AS, KIR-2DL4, KIR103, KIR103AS,ATGP3639-10ug,ATGP3639-20ug,ATGP3639-50ug,ATGP3639-100ug,ATGP3639-250ug,ATGP3639-500ug,ATGP3639-1mg,ATGP3639-10,ATGP3639-20,ATGP3639-50,ATGP3639-100,ATGP3639-250,ATGP3639-500,ATGP3639-1

more info or order :

NKMAX product webpage