product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human B7-H3 (4Ig)/B7-H3b protein
catalog :
ATGP3635
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human B7-H3 (4Ig)/B7-H3b protein
Domain :
29-466aa
Catalog number (SKU) :
ATGP3635
NCBI :
NP_001019907.1
Description :
CD276, also known as CD276 antigen isoform, is a member of B7 family of immunoregulatory transmembrane glycoproteins expressed by T cells. It is a costimulatory molecule for T cell activation and IFN-gamma production. It upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu. It is correlated with TNM stage of NSCLC and may serve as a potential biomarker for NSCLC-derived MPEs. Recombinant human CD276, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
CD276 antigen isoform, CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Sun ZZ., et al. (2016) Oncol Rep. 36:231-238.;; Chen L., et al. (2016) Clin Chim Acta. 457:81-85.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
48.1 kDa (446aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
LEVQVPEDPV VALVGTDATL CCSFSPEPGF SLAQLNLIWQ LTDTKQLVHS FAEGQDQGSA YANRTALFPD LLAQGNASLR LQRVRVADEG SFTCFVSIRD FGSAAVSLQV AAPYSKPSMT LEPNKDLRPG DTVTITCSSY QGYPEAEVFW QDGQGVPLTG NVTTSQMANE QGLFDVHSIL RVVLGANGTY SCLVRNPVLQ QDAHSSVTIT PQRSPTGAVE VQVPEDPVVA LVGTDATLRC SFSPEPGFSL AQLNLIWQLT DTKQLVHSFT EGRDQGSAYA NRTALFPDLL AQGNASLRLQ RVRVADEGSF TCFVSIRDFG SAAVSLQVAA PYSKPSMTLE PNKDLRPGDT VTITCSSYRG YPEAEVFWQD GQGVPLTGNV TTSQMANEQG LFDVHSVLRV VLGANGTYSC LVRNPVLQQD AHGSVTITGQ PMTFPPEA
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Leu29
Product Type Name :
Recombinant Protein
UniProt No. :
Q5ZPR3
Internal Search Terms :
B7-H3 (4Ig), B7-H3b, CD276 antigen isoform, CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2,ATGP3635-10ug,ATGP3635-20ug,ATGP3635-50ug,ATGP3635-100ug,ATGP3635-250ug,ATGP3635-500ug,ATGP3635-1mg,ATGP3635-10,ATGP3635-20,ATGP3635-50,ATGP3635-100,ATGP3635-250,ATGP3635-500,ATGP3635-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.