product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human N-Cadherin/CDH2 protein
catalog :
ATGP3634
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human N-Cadherin/CDH2 protein
Domain :
160-724aa
Catalog number (SKU) :
ATGP3634
NCBI :
NP_001783
Description :
CDH2, also known as cadherin-2 isoform 1, is a transmembrane, homophilic glycoprotein belonging to the calcium-dependent cell adhesion molecule family. It plays a role in neurons and later was found to also play a role in cardiac muscle and in cancer metastasis. Its loss promotes tumorigenesis by releasing membrane-bound B-catenin, hence stimulating Wnt signaling. It seems to be involved in tumor development, but this finding is limited in adrenocortical tumors (ACTs). Recombinant human CDH2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Cadherin-2 isoform 1, CDH2, CD325, CDHN, CDw325, NCAD, Neural cadherin
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Buxton RS., et al. (1992) Semin Cell Biol. 3:157-167.;; Rubin B., et al. (2016) Tumour Biol. 37:13545-13555.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
62.9 kDa (574aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
ADPDWVIPPI NLPENSRGPF PQELVRIRSD RDKNLSLRYS VTGPGADQPP TGIFIINPIS GQLSVTKPLD REQIARFHLR AHAVDINGNQ VENPIDIVIN VIDMNDNRPE FLHQVWNGTV PEGSKPGTYV MTVTAIDADD PNALNGMLRY RIVSQAPSTP SPNMFTINNE TGDIITVAAG LDREKVQQYT LIIQATDMEG NPTYGLSNTA TAVITVTDVN DNPPEFTAMT FYGEVPENRV DIIVANLTVT DKDQPHTPAW NAVYRISGGD PTGRFAIQTD PNSNDGLVTV VKPIDFETNR MFVLTVAAEN QVPLAKGIQH PPQSTATVSV TVIDVNENPY FAPNPKIIRQ EEGLHAGTML TTFTAQDPDR YMQQNIRYTK LSDPANWLKI DPVNGQITTI AVLDRESPNV KNNIYNATFL ASDNGIPPMS GTGTLQIYLL DINDNAPQVL PQEAETCETP DPNSINITAL DYDIDPNAGP FAFDLPLSPV TIKRNWTITR LNGDFAQLNL KIKFLEAGIY EVPIIITDSG NPPKSNISIL RVKVCQCDSN GDCTDVDRIV GAGLGTGAHH HHHH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P19022
Internal Search Terms :
N-Cadherin, Cadherin-2 isoform 1, CDH2, CD325, CDHN, CDw325, NCAD,ATGP3634-10ug,ATGP3634-20ug,ATGP3634-50ug,ATGP3634-100ug,ATGP3634-250ug,ATGP3634-500ug,ATGP3634-1mg,ATGP3634-10,ATGP3634-20,ATGP3634-50,ATGP3634-100,ATGP3634-250,ATGP3634-500,ATGP3634-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.