Recombinant human PD-L1/B7-H1 protein | NKMAX ATGP3631 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PD-L1/B7-H1 protein

catalog :

ATGP3631

quantity :

10 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PD-L1/B7-H1 protein

Domain :

19-238aa

Catalog number (SKU) :

ATGP3631

NCBI :

NP_054862.1

Description :

CD274, also known as programmed cell death 1 ligand 1 isoform, is a member of the growing B7 family of immune molecules. This protein is involved in the regulation of cellular and humoral immune responses. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells. Also, it plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development. Recombinant human CD274, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Programmed cell death 1 ligand 1 isoform, CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dong H., et al, (1999) Nat. Med. 5:1365-1369.;; Trabattoni D., et al, (2003) Blood 101:2514-2520.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human PD-1 (CAT# ATGP4027). The ED50 range ≤ 0.5 ug/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

52.5 kDa (462aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human PD-1 (CAT# ATGP4027) is coated at 5 ug/ml (100 ul/well) can bind Human PD-L1. The ED50 range ≤ 0.5 ug/ml.

Amino Acid Sequence :

FTVTVPK DLYVVEYGSN MTIECKFPVE KQLDLAALIV YWEMEDKNII QFVHGEEDLK VQHSSYRQRA RLLKDQLSLG NAALQITDVK LQDAGVYRCM ISYGGADYKR ITVKVNAPYN KINQRILVVD PVTSEHELTC QAEGYPKAEV IWTSSDHQVL SGKTTTTNSK REEKLFNVTS TLRINTTTNE IFYCTFRRLD PEENHTAELV IPELPLAHPP NER

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NZQ7

Internal Search Terms :

PD-L1, B7-H1, Programmed cell death 1 ligand 1 isoform, CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1,ATGP3631-10ug,ATGP3631-20ug,ATGP3631-50ug,ATGP3631-100ug,ATGP3631-250ug,ATGP3631-500ug,ATGP3631-1mg,ATGP3631-10,ATGP3631-20,ATGP3631-50,ATGP3631-100,ATGP3631-250,ATGP3631-500,ATGP3631-1

more info or order :

NKMAX product webpage