protein

Recombinant human PD-1 protein

ATGP3612

10 ug

80 USD

Recombinant human PD-1 protein

21-170aa

ATGP3612

NP_005009.2

PDCD1, also known as programmed cell death protein 1, is a type 1 transmembrane glycoprotein, and is an immune-receptor belonging to the CD28/CTLA4 family. This protein is expressed on the surface of activated T-cell, B-cell, macrophages, myeloid cells and subset of thymocytes. Also, it inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4 and IL-10. As a cell surface molecule, it regulates the adaptive immune response. Recombinant human PDCD1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Programmed cell death protein 1, PDCD1, CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2

0.5mg/ml (determined by absorbance at 280nm)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Ishida Y., et al, (1992) EMBO J. 11:3887-3895.;; Lastwika KJ., et al, (2016) Cancer Res. 76:227-238.

> 90% by SDS-PAGE

SDS-PAGE

Human

Apoptosis

44 kDa (392aa)

< 1 EU per 1ug of protein (determined by LAL method)

PGWFLDS PDRPWNPPTF SPALLVVTEG DNATFTCSFS NTSESFVLNW YRMSPSNQTD KLAAFPEDRS QPGQDCRFRV TQLPNGRDFH MSVVRARRND SGTYLCGAIS LAPKAQIKES LRAELRVTER RAEVPTAHPS PSPRPAGQFQ TLV

hIgG-His-Tag

Baculovirus

Ala

Recombinant Protein

Q15116

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