Recombinant human TFPI protein | NKMAX ATGP3609 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TFPI protein

catalog :

ATGP3609

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TFPI protein

Domain :

29-304aa

Catalog number (SKU) :

ATGP3609

NCBI :

NP_006278.1

Description :

TFPI, also known as tissue factor pathway inhibitor isoform, is the major regulator of tissue factor (TF) -induced coagulation. It is predominantly produced by microvascular endothelial cells, though it is also found in platelets, monocytes, smooth muscle cells, and plasma. It is an anticoagulant protein that inhibits early phases of the procoagulant response. It has been shown to be associated with breast cancer pathogenesis. It consists of a highly negatively charged amino-terminus, three tandemly linked Kunitz domains, and a highly positively charged carboxy-terminus. It exhibits significant homology with human inter-alpha-trypsin inhibitor and bovine basic pancreatic trypsin inhibitor. Recombinant human TFPI, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tissue factor pathway inhibitor isoform, TFPI, EPI, LACI, TFI, TFPI1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Maroney SA., et al. (2010) Thromb Res. 1:S52-S56.;; Ali HO., et al. (2016) PLoS One. 11:e0152114.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

33 kDa (285aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

DSEEDEE HTIITDTELP PLKLMHSFCA FKADDGPCKA IMKRFFFNIF TRQCEEFIYG GCEGNQNRFE SLEECKKMCT RDNANRIIKT TLQQEKPDFC FLEEDPGICR GYITRYFYNN QTKQCERFKY GGCLGNMNNF ETLEECKNIC EDGPNGFQVD NYGTQLNAVN NSLTPQSTKV PSLFEFHGPS WCLTPADRGL CRANENRFYY NSVIGKCRPF KYSGCGGNEN NFTSKQECLR ACKKGFIQRI SKGGLIKTKR KRKKQRVKIA YEEIFVKNM

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P10646

Internal Search Terms :

TFPI, Tissue factor pathway inhibitor isoform, TFPI, EPI, LACI, TFI, TFPI1,ATGP3609-10ug,ATGP3609-20ug,ATGP3609-50ug,ATGP3609-100ug,ATGP3609-250ug,ATGP3609-500ug,ATGP3609-1mg,ATGP3609-10,ATGP3609-20,ATGP3609-50,ATGP3609-100,ATGP3609-250,ATGP3609-500,ATGP3609-1

more info or order :

NKMAX product webpage