Recombinant mouse Cyclophilin B/PPIB protein | NKMAX ATGP3599 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Cyclophilin B/PPIB protein

catalog :

ATGP3599

quantity :

10 ug

price :

45 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Cyclophilin B/PPIB protein

Domain :

34-216aa

Catalog number (SKU) :

ATGP3599

NCBI :

NP_035279

Description :

Ppib, also known as peptidyl-prolyl cis-trans isomerase B, is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A -mediated immunosuppression. Recombinant mouse Ppib, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Peptidyl-prolyl cis-trans isomerase B, Peptidylprolyl isomerase B, PPIase B, Cphn-2, Cyclophilin B, CYP-20b, CYPB, CYP-S1, OI9, Rotamase B, S-cyclophilin, SCYLP

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Obata Y, et al. (2005) J Biol Chem. 280(18):18355-60;; Denys A , et al. (1997) Immunology. 91(4):609-17.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 1,000nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Mouse

Gene Category :

Cell Cycle

Molecular Weight :

22.7 kDa (207aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 1,000 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Amino Acid Sequence :

NDKKKG PKVTVKVYFD LQIGDESVGR VVFGLFGKTV PKTVDNFVAL ATGEKGFGYK NSKFHRVIKD FMIQGGDFTR GDGTGGKSIY GERFPDENFK LKHYGPGWVS MANAGKDTNG SQFFITTVKT SWLDGKHVVF GKVLEGMDVV RKVESTKTDS RDKPLKDVII VDSGKIEVEK PFAIAKE

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P24369

Internal Search Terms :

26- 216aa, 26-216aa, AA408962, AA553318, AI844835, Cphn 2, Cphn2, Cphn-2, Cyclophilin B, Cyclophilin-B, CyclophilinB, CyP 20b, CyP-20b, CyP20b, CYP S1, CYP-S1, CYPS1, CYPB, CYP-S1: Cyclophilin-B, MGC14109, MGC2224, Peptidyl prolyl cis trans isomerase B, Peptidyl prolyl cis trans isomerase B precursor, Peptidyl-prolyl cis-trans isomerase B, Peptidylprolyl isomerase B, PPIase, PPIB, Rotamase, S cyclophilin, SCYLP, ATGP3599-10ug, ATGP3599-20ug, ATGP3599-50ug, ATGP3599-100ug, ATGP3599-250ug, ATGP3599-500ug, ATGP3599-1mg, ATGP3599-010, ATGP3599-020, ATGP3599-050, ATGP3599-100, ATGP3599-250, ATGP3599-500, ATGP3599-01M

more info or order :

NKMAX product webpage