Recombinant human IL-23 protein | NKMAX ATGP3598 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-23 protein

catalog :

ATGP3598

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-23 protein

Domain :

23-328aa(p40)/20-189aa(p19)

Catalog number (SKU) :

ATGP3598

NCBI :

NP_002178(p40)NP_057668(p19)

Description :

IL23 p40 and p19, also known as interleukin-12 subunit beta/interleukin-23 subunit alpha, is a heterodimeric cytokine composed of two disulfide-linked subunit, a p19 subunit that is unique to IL23, and a p40 subunit that is shared with IL12. The p19 subunit has homology to the p35 subunit of IL12, as well as to other single chain sytokines sub as IL6 and IL11. It is produced by macrophages and B lymphocytes and has multiple effects on T-cells and NK cells, including stimulation of cytotoxic activity, proliferation, and promotion of Th1 development as well as IFN-gamma and TNF production. Recombinant human IL23 p40 and p19, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-12 subunit beta / Interleukin-23 subunit alpha, CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2/ IL-23, IL-23A, IL23P19, P19, SGRF

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Oppmann B., et al, (2000) Immunity. 13:715-25.;; Parham C., et al, (2002) J. lmmunol. 168:5699-708.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

34.6 kDa (p40, 306aa);;19.5 kDa (p19, 176aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

IL12B(p40);;IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS;;IL23A(p19);;RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ile23, Arg20

Product Type Name :

Recombinant Protein

UniProt No. :

P29460(p40)/Q9NPF7(p19)

Internal Search Terms :

IL23,ATGP3598-10ug,ATGP3598-20ug,ATGP3598-50ug,ATGP3598-100ug,ATGP3598-250ug,ATGP3598-500ug,ATGP3598-1mg,ATGP3598-10,ATGP3598-20,ATGP3598-50,ATGP3598-100,ATGP3598-250,ATGP3598-500,ATGP3598-1

more info or order :

NKMAX product webpage