Recombinant human SRSF1 protein | NKMAX ATGP3558 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SRSF1 protein

catalog :

ATGP3558

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SRSF1 protein

Domain :

1-248aa

Catalog number (SKU) :

ATGP3558

NCBI :

NP_008855

Description :

SRSF1, also known as Serine/arginine-rich splicing factor 1, is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. This protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. In addition to being involved in the splicing process, it also mediates post-splicing activities, such as mRNA nuclear export and translation. Recombinant human SRSF1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Serine/arginine-rich splicing factor 1, SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a

Concentration :

0.25mg/ml (determined by Bradford Assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM KCl, 1mM DTT, 0.2mM EDTA, 40% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Xue F., et al. (2015) PLoS One. 10: e0115354.;; Goncalves V., et al. (2014) RNA. 20:474-482.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

28.5 kDa (254aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MSGGGVIRGP AGNNDCRIYV GNLPPDIRTK DIEDVFYKYG AIRDIDLKNR RGGPPFAFVE FEDPRDAEDA VYGRDGYDYD GYRLRVEFPR SGRGTGRGGG GGGGGGAPRG RYGPPSRRSE NRVVVSGLPP SGSWQDLKDH MREAGDVCYA DVYRDGTGVV EFVRKEDMTY AVRKLDNTKF RSHEGETAYI RVKVDGPRSP SYGRSRSRSR SRSRSRSRSN SRSRSYSPRR SRGSPRYSPR HSRSRSRTHH HHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Met1

Product Type Name :

Recombinant Protein

UniProt No. :

Q07955

Internal Search Terms :

SRSF1, Serine/arginine-rich splicing factor 1, SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a,ATGP3558-10ug,ATGP3558-20ug,ATGP3558-50ug,ATGP3558-100ug,ATGP3558-250ug,ATGP3558-500ug,ATGP3558-1mg,ATGP3558-10,ATGP3558-20,ATGP3558-50,ATGP3558-100,ATGP3558-250,ATGP3558-500,ATGP3558-1

more info or order :

NKMAX product webpage