Recombinant human 2B4/CD244 protein | NKMAX ATGP3552 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human 2B4/CD244 protein

catalog :

ATGP3552

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human 2B4/CD244 protein

Domain :

19-224aa

Catalog number (SKU) :

ATGP3552

NCBI :

NP_057466.1

Description :

CD244, also known as natural killer cell receptor 2B4 isoform 1, is a natural killer and T cell immunoglobulin superfamily surface protein and ligand of CD48. It is a cell surface glycoprotein related to CD2 and implicated in the regulation of natural killer and T lymphocyte function. It is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. It activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness. Recombinant human CD244, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CD244 molecule natural killer cell receptor 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Brown MH., et al. (1998) J Exp Med. 188:2083-2090.;; Chuang SS., et al. (2001) J Immunol. 167:6210-6216.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human CD48/SLAMF2 (CAT# ATGP3642). The ED50 range ≤ 0.1 ug/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

50.2 kDa (448aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human CD48/SLAMF2 (CAT# ATGP3642) is coated at 2 ug/ml (100 ul/well) can bind Human CD244. The ED50 range ≤ 0.1 ug/ml.

Amino Acid Sequence :

GKGCQGS ADHVVSISGV PLQLQPNSIQ TKVDSIAWKK LLPSQNGFHH ILKWENGSLP SNTSNDRFSF IVKNLSLLIK AAQQQDSGLY CLEVTSISGK VQTATFQVFV FDKVEKPRLQ GQGKILDRGR CQVALSCLVS RDGNVSYAWY RGSKLIQTAG NLTYLDEEVD INGTHTYTCN VSNPVSWESH TLNLTQDCQN AHQEFRFWP

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BZW8

Internal Search Terms :

SLAMF4, Nmrk, NKR2B4, Natural killer cell receptor 2B4 isoform 1, natural killer cell receptor 2B4, NAIL, CD244 molecule natural killer cell receptor 2B4, CD244 molecule, CD244, 2B4, ATGP3552-10ug, ATGP3552-20ug, ATGP3552-50ug, ATGP3552-100ug, ATGP3552-250ug, ATGP3552-500ug, ATGP3552-1mg, ATGP3552-010, ATGP3552-020, ATGP3552-050, ATGP3552-100, ATGP3552-250, ATGP3552-500, ATGP3552-01M

more info or order :

NKMAX product webpage