protein

Recombinant human Relaxin-2 protein

ATGP3545

4 ug

80 USD

Recombinant human Relaxin-2 protein

25-185aa

ATGP3545

NP_604390

RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18 kDa in size and 185 aa in length. It contains a 24 aa signal sequence, a 3. 3 kDa, 29 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2. 7 kDa, 24 aa A domain. Recombinant human RLN2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Prorelaxin H2 isoform 1, RLN2, bA12D24.1.1, bA12D24.1.2, H2, H2-RLX, RLXH2

0.5mg/ml (determined by absorbance at 280nm)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Ng TM., et al, (2016) Cardiol Rev. 24:194-204.;; Sherwood OD., et al, (2004) Endocr. Rev. 25:205-234.

> 85% by SDS-PAGE

SDS-PAGE

Human

Signal Transduction

19.3 kDa (170aa)

< 1 EU per 1ug of protein (determined by LAL method)

ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH

His-Tag

Baculovirus

Ala

Recombinant Protein

P04090

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