product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ALK-3/BMPR1A protein
catalog :
ATGP3541
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ALK-3/BMPR1A protein
Domain :
24-152aa
Catalog number (SKU) :
ATGP3541
NCBI :
NP_004320
Description :
BMPR1A, also known as bone morphogenetic protein receptor type-1A, is secreted cytokines/growth factors belonging to the Transforming Growth Factor beta (TGFbeta) family. It has been shown to be overexpressed in human breast cancers. Its deletion impairs mammary tumor formation and metastasis. It plays important roles in the differentiation and development of neurons. Its expression is up-regulated during bone formation, and that they may play important roles in bone morphogenesis. Recombinant human BMPR1A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Bone morphogenetic protein receptor type 1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292, ACVRLK3, ALK3
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Pickup MW., et al. (2015) Oncotarget. 6:22890-22904.;; Wang W., et al. (2014) Int J Clin Exp Pathol. 7:2312-2318.;; Ishidou Y., et al. (1995) J Bone Miner Res. 10:1651-1659.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
41.4 kDa (371aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
ADPQNLDSML HGTGMKSDSD QKKSENGVTL APEDTLPFLK CYCSGHCPDD AINNTCITNG HCFAIIEEDD QGETTLASGC MKYEGSDFQC KDSPKAQLRR TIECCRTNLC NQYLQPTLPP VVIGPFFDGS IRLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P36894
Internal Search Terms :
BMPR-IA, ALK3, Bone morphogenetic protein receptor type-1A, BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5,ATGP3541-10ug,ATGP3541-20ug,ATGP3541-50ug,ATGP3541-100ug,ATGP3541-250ug,ATGP3541-500ug,ATGP3541-1mg,ATGP3541-10,ATGP3541-20,ATGP3541-50,ATGP3541-100,ATGP3541-250,ATGP3541-500,ATGP3541-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.